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Structural and biochemical analysis of a thermostable membrane-bound stomatin-specific protease
Membrane-bound proteases are involved in various regulatory functions. The N-terminal region of PH1510p (1510-N) from the hyperthermophilic archaeon Pyrococcus horikoshii is a serine protease with a catalytic Ser–Lys dyad (Ser97 and Lys138), and specifically cleaves the C-terminal hydrophobic region...
Autores principales: | Yokoyama, Hideshi, Kobayashi, Daisuke, Takizawa, Naoto, Fujii, Satoshi, Matsui, Ikuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795559/ https://www.ncbi.nlm.nih.gov/pubmed/24121343 http://dx.doi.org/10.1107/S0909049513021328 |
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