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Susceptibility to Cutaneous Squamous Cell Carcinoma in Renal Transplant Recipients Associates with Genes Regulating Melanogenesis Independent of their Role in Pigmentation

The highly polymorphic melanocortin 1 receptor (MC1R) gene plays a crucial role in pigmentation. Variants of the gene have been implicated in risk of cutaneous squamous cell carcinoma (SCC) in the general population. In renal transplant (RT) recipients these cancers are more aggressive and very comm...

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Detalles Bibliográficos
Autores principales: Andresen, Per A., Nymoen, Dag A., Kjærheim, Kristina, Leivestad, Torbjørn, Helsing, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795574/
https://www.ncbi.nlm.nih.gov/pubmed/24179397
http://dx.doi.org/10.4137/BIC.S12754