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Roles of TLR7 in Activation of NF-κB Signaling of Keratinocytes by Imiquimod

Imiquimod is known to exert its effects through Toll-like receptor 7 (TLR7) and/or TLR8, resulting in expression of proinflammatory cytokines and chemokines. Keratinocytes have not been reported to constitutively express TLR7 and TLR8, and the action of imiquimod is thought to be mediated by the ade...

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Detalles Bibliográficos
Autores principales: Li, Zheng Jun, Sohn, Kyung-Cheol, Choi, Dae-Kyoung, Shi, Ge, Hong, Dongkyun, Lee, Han-Eul, Whang, Kyu Uang, Lee, Young Ho, Im, Myung, Lee, Young, Seo, Young-Joon, Kim, Chang Deok, Lee, Jeung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795621/
https://www.ncbi.nlm.nih.gov/pubmed/24146965
http://dx.doi.org/10.1371/journal.pone.0077159