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Toxicity and Immunogenicity of Enterotoxigenic Escherichia coli Heat-Labile and Heat-Stable Toxoid Fusion 3xSTa(A14Q)-LT(S63K/R192G/L211A) in a Murine Model

Diarrhea is the second leading cause of death to young children. Enterotoxigenic Escherichia coli (ETEC) are the most common bacteria causing diarrhea. Adhesins and enterotoxins are the virulence determinants in ETEC diarrhea. Adhesins mediate bacterial attachment and colonization, and enterotoxins...

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Detalles Bibliográficos
Autores principales: Zhang, Chengxian, Knudsen, David E., Liu, Mei, Robertson, Donald C., Zhang, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795625/
https://www.ncbi.nlm.nih.gov/pubmed/24146989
http://dx.doi.org/10.1371/journal.pone.0077386