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Genetic Variation in a MicroRNA-502 Minding Site in SET8 Gene Confers Clinical Outcome of Non-Small Cell Lung Cancer in a Chinese Population

BACKGROUND: Genetic variants may influence microRNA-target interaction through modulate their binding affinity, creating or destroying miRNA-binding sites. SET8, a member of the SET domain-containing methyltransferase, has been implicated in a variety array of biological processes. METHODS: Using Ta...

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Detalles Bibliográficos
Autores principales: Xu, Jiali, Yin, Zhiqiang, Gao, Wen, Liu, Lingxiang, Yin, Yongmei, Liu, Ping, Shu, Yongqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795636/
https://www.ncbi.nlm.nih.gov/pubmed/24146953
http://dx.doi.org/10.1371/journal.pone.0077024