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Genetic Variation in a MicroRNA-502 Minding Site in SET8 Gene Confers Clinical Outcome of Non-Small Cell Lung Cancer in a Chinese Population
BACKGROUND: Genetic variants may influence microRNA-target interaction through modulate their binding affinity, creating or destroying miRNA-binding sites. SET8, a member of the SET domain-containing methyltransferase, has been implicated in a variety array of biological processes. METHODS: Using Ta...
Autores principales: | Xu, Jiali, Yin, Zhiqiang, Gao, Wen, Liu, Lingxiang, Yin, Yongmei, Liu, Ping, Shu, Yongqian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795636/ https://www.ncbi.nlm.nih.gov/pubmed/24146953 http://dx.doi.org/10.1371/journal.pone.0077024 |
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