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Autoantibodies against the β(3)-Adrenoceptor Protect from Cardiac Dysfunction in a Rat Model of Pressure Overload
β(3)-adrenoceptors (β(3)-ARs) mediate a negative inotropic effect in human ventricular cardiomyocytes, which is opposite to that of β(1)- and β(2)-ARs. It has been previously demonstrated that autoantibodies against the β(1/)β(2)-AR exist in the sera of some patients with heart failure (HF) and thes...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795652/ https://www.ncbi.nlm.nih.gov/pubmed/24147120 http://dx.doi.org/10.1371/journal.pone.0078207 |