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Targeted Deletion of FGL2 Leads to Increased Early Viral Replication and Enhanced Adaptive Immunity in a Murine Model of Acute Viral Hepatitis Caused by LCMV WE

Mounting effective innate and adaptive immune responses are critical for viral clearance and the generation of long lasting immunity. It is known that production of inhibitory factors may result in the inability of the host to clear viruses, resulting in chronic viral persistence. Fibrinogen-like pr...

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Detalles Bibliográficos
Autores principales: Khattar, Ramzi, Luft, Olga, Yavorska, Nataliya, Shalev, Itay, Phillips, M. James, Adeyi, Oyedele, Gao, Darrin, Bartczak, Agata, Urbanellis, Peter, Shyu, Wendy, Zhang, Jianhua, Manuel, Justin, Levy, Gary A., Selzner, Nazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795679/
https://www.ncbi.nlm.nih.gov/pubmed/24146739
http://dx.doi.org/10.1371/journal.pone.0072309