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Targeted Deletion of FGL2 Leads to Increased Early Viral Replication and Enhanced Adaptive Immunity in a Murine Model of Acute Viral Hepatitis Caused by LCMV WE
Mounting effective innate and adaptive immune responses are critical for viral clearance and the generation of long lasting immunity. It is known that production of inhibitory factors may result in the inability of the host to clear viruses, resulting in chronic viral persistence. Fibrinogen-like pr...
Autores principales: | Khattar, Ramzi, Luft, Olga, Yavorska, Nataliya, Shalev, Itay, Phillips, M. James, Adeyi, Oyedele, Gao, Darrin, Bartczak, Agata, Urbanellis, Peter, Shyu, Wendy, Zhang, Jianhua, Manuel, Justin, Levy, Gary A., Selzner, Nazia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795679/ https://www.ncbi.nlm.nih.gov/pubmed/24146739 http://dx.doi.org/10.1371/journal.pone.0072309 |
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