p53-Mediated Biliary Defects Caused by Knockdown of cirh1a, the Zebrafish Homolog of the Gene Responsible for North American Indian Childhood Cirrhosis

North American Indian Childhood Cirrhosis (NAIC) is a rare, autosomal recessive, progressive cholestatic disease of infancy affecting the Cree-Ojibway first Nations of Quebec. All NAIC patients are homozygous for a missense mutation (R565W) in CIRH1A, the human homolog of the yeast nucleolar protein...

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Detalles Bibliográficos
Autores principales: Wilkins, Benjamin J., Lorent, Kristin, Matthews, Randolph P., Pack, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795688/
https://www.ncbi.nlm.nih.gov/pubmed/24147052
http://dx.doi.org/10.1371/journal.pone.0077670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795688/
https://www.ncbi.nlm.nih.gov/pubmed/24147052
http://dx.doi.org/10.1371/journal.pone.0077670

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