IL-17A and IL-2-Expanded Regulatory T Cells Cooperate to Inhibit Th1-Mediated Rejection of MHC II Disparate Skin Grafts

Several evidences suggest that regulatory T cells (Treg) promote Th17 differentiation. Based on this hypothesis, we tested the effect of IL-17A neutralization in a model of skin transplantation in which long-term graft survival depends on a strong in vivo Treg expansion induced by transient exogenou...

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Detalles Bibliográficos
Autores principales: Vokaer, Benoît, Charbonnier, Louis-Marie, Lemaître, Philippe H., Spilleboudt, Chloé, Le Moine, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795694/
https://www.ncbi.nlm.nih.gov/pubmed/24146810
http://dx.doi.org/10.1371/journal.pone.0076040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795694/
https://www.ncbi.nlm.nih.gov/pubmed/24146810
http://dx.doi.org/10.1371/journal.pone.0076040

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