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Direct Visualization of the Highly Polymorphic RNU2 Locus in Proximity to the BRCA1 Gene

Although the breast cancer susceptibility gene BRCA1 is one of the most extensively characterized genetic loci, much less is known about its upstream variable number tandem repeat element, the RNU2 locus. RNU2 encodes the U2 small nuclear RNA, an essential splicing element, but this locus is missing...

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Detalles Bibliográficos
Autores principales: Tessereau, Chloé, Buisson, Monique, Monnet, Nastasia, Imbert, Marine, Barjhoux, Laure, Schluth-Bolard, Caroline, Sanlaville, Damien, Conseiller, Emmanuel, Ceppi, Maurizio, Sinilnikova, Olga M., Mazoyer, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795722/
https://www.ncbi.nlm.nih.gov/pubmed/24146815
http://dx.doi.org/10.1371/journal.pone.0076054