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Direct Visualization of the Highly Polymorphic RNU2 Locus in Proximity to the BRCA1 Gene
Although the breast cancer susceptibility gene BRCA1 is one of the most extensively characterized genetic loci, much less is known about its upstream variable number tandem repeat element, the RNU2 locus. RNU2 encodes the U2 small nuclear RNA, an essential splicing element, but this locus is missing...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795722/ https://www.ncbi.nlm.nih.gov/pubmed/24146815 http://dx.doi.org/10.1371/journal.pone.0076054 |