Deferred Pre-Emptive Switch from Calcineurin Inhibitor to Sirolimus Leads to Improvement in GFR and Expansion of T Regulatory Cell Population: A Randomized, Controlled Trial

BACKGROUND: Measures to prevent chronic calcineurin inhibitor (CNI) toxicity have included limiting exposure by switching to sirolimus (SIR). SIR may favorably influence T regulator cell (T(reg)) population. This randomized controlled trial compares the effect of switching from CNI to SIR on glomeru...

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Detalles Bibliográficos
Autores principales: Bansal, Dinesh, Yadav, Ashok K., Kumar, Vinod, Minz, Mukut, Sakhuja, Vinay, Jha, Vivekanand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795731/
https://www.ncbi.nlm.nih.gov/pubmed/24146762
http://dx.doi.org/10.1371/journal.pone.0075591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795731/
https://www.ncbi.nlm.nih.gov/pubmed/24146762
http://dx.doi.org/10.1371/journal.pone.0075591

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