Establishment of an In Vitro Transport Assay That Reveals Mechanistic Differences in Cytosolic Events Controlling Cholera Toxin and T-Cell Receptor α Retro-Translocation

Following retrograde trafficking to the endoplasmic reticulum (ER), cholera toxin A1 (CTA1) subunit hijacks ER-associated degradation (ERAD) machinery and retro-translocates into the cytosol to induce toxicity. We previously established a cell-based in vivo assay to identify ER components that regul...

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Detalles Bibliográficos
Autores principales: Moore, Paul, He, Kaiyu, Tsai, Billy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795749/
https://www.ncbi.nlm.nih.gov/pubmed/24146777
http://dx.doi.org/10.1371/journal.pone.0075801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795749/
https://www.ncbi.nlm.nih.gov/pubmed/24146777
http://dx.doi.org/10.1371/journal.pone.0075801

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