Nature-inspired design of motif-specific antibody scaffolds

Aberrant changes in post-translational modifications (PTMs) such as phosphorylation underlie a majority of human diseases. However, detection and quantification of PTMs for diagnostic or biomarker applications often requires monoclonal PTM-specific antibodies, which are challenging to generate using...

Descripción completa

Detalles Bibliográficos
Autores principales: Koerber, James T., Thomsen, Nathan D., Hannigan, Brett T., Degrado, William F., Wells, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795957/
https://www.ncbi.nlm.nih.gov/pubmed/23955275
http://dx.doi.org/10.1038/nbt.2672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795957/
https://www.ncbi.nlm.nih.gov/pubmed/23955275
http://dx.doi.org/10.1038/nbt.2672

Ejemplares similares