Triptolide avoids cisplatin resistance and induces apoptosis via the reactive oxygen species/nuclear factor-κB pathway in SKOV3(PT) platinum-resistant human ovarian cancer cells

An acquired resistance to platinum-based drugs has emerged as a significant impediment to effective ovarian cancer therapy. The present study explored the anticancer mechanisms of triptolide (TPL) in SKOV3(PT) platinum-resistant human ovarian cancer cells and observed that TPL activated caspase 3 an...

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Detalles Bibliográficos
Autores principales: ZHONG, YAN-YING, CHEN, HE-PING, TAN, BU-ZHEN, YU, HAI-HONG, HUANG, XIAO-SHAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796418/
https://www.ncbi.nlm.nih.gov/pubmed/24137468
http://dx.doi.org/10.3892/ol.2013.1524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796418/
https://www.ncbi.nlm.nih.gov/pubmed/24137468
http://dx.doi.org/10.3892/ol.2013.1524

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