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Jagged1 contributes to the drug resistance of Jurkat cells in contact with human umbilical cord-derived mesenchymal stem cells

Notch signaling, which is driven by the Notch1 receptor, plays an essential role in the pathogenesis and stroma-mediated drug resistance of T-cell acute lymphoblastic leukemia (T-ALL). However, little is known about the roles of Notch ligands in the survival or drug resistance of T-ALL cells. In the...

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Detalles Bibliográficos
Autores principales: YUAN, YIN, LU, XIN, CHEN, XUAN, SHAO, HONGWEI, HUANG, SHULIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796424/
https://www.ncbi.nlm.nih.gov/pubmed/24137453
http://dx.doi.org/10.3892/ol.2013.1523