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Inhibition of tumor growth and histopathological changes following treatment with a chemokine receptor CXCR4 antagonist in a prostate cancer xenograft model

The stromal derived factor-1 (SDF-1)/CXCR4 axis is associated with tumor aggressiveness and metastasis in prostate cancer. The present study aimed to explore the potential therapeutic effects of a CXCR4 antagonist in prostate cancer. The effect of SDF-1 and a CXCR4-specific antagonist, AMD3100, on h...

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Detalles Bibliográficos
Autores principales: CHO, KANG SU, YOON, SO JUNG, LEE, JOO YONG, CHO, NAM HOON, CHOI, YOUNG DEUK, SONG, YUN SEOB, HONG, SUNG JOON
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796427/
https://www.ncbi.nlm.nih.gov/pubmed/24137439
http://dx.doi.org/10.3892/ol.2013.1515