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PIAS3 promotes homology-directed repair and distal non-homologous end joining

A DNA double-strand break (DSB) is the most severe form of DNA damage and is mainly repaired through homologous recombination (HR), which has a high fidelity, or non-homologous end joining (NHEJ), which is prone to errors. Defects in the DNA damage response lead to genomic instability and ultimately...

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Detalles Bibliográficos
Autores principales: LIU, SHICUI, FAN, ZHONGYI, GENG, ZHENGYING, ZHANG, HAO, YE, QINONG, JIAO, SHUNCHANG, XU, XIAOJIE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796434/
https://www.ncbi.nlm.nih.gov/pubmed/24137461
http://dx.doi.org/10.3892/ol.2013.1472