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Ankyrin-G Participates in I(Na) Remodeling in Myocytes from the Border Zones of Infarcted Canine Heart

Cardiac Na channel remodeling provides a critical substrate for generation of reentrant arrhythmias in border zones of the infarcted canine heart. Recent studies show that Na(v)1.5 assembly and function are linked to ankyrin-G, gap, and mechanical junction proteins. In this study our objective is to...

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Detalles Bibliográficos
Autores principales: Dun, Wen, Lowe, John S., Wright, Patrick, Hund, Thomas J., Mohler, Peter J., Boyden, Penelope A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796465/
https://www.ncbi.nlm.nih.gov/pubmed/24155982
http://dx.doi.org/10.1371/journal.pone.0078087