PKCδ Localization at the Membrane Increases Matrix Traction Force Dependent on PLCγ1/EGFR Signaling

INTRODUCTION: During wound healing, fibroblasts initially migrate into the wound bed and later contract the matrix. Relevant mediators of transcellular contractility revealed by systems analyses are protein kinase c delta/myosin light chain-2 (PKCδ/MLC-2). PKCδ is activated by growth factor-driven P...

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Detalles Bibliográficos
Autores principales: Jamison, Joshua, Lauffenburger, Douglas, Wang, James C.-H., Wells, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796482/
https://www.ncbi.nlm.nih.gov/pubmed/24155954
http://dx.doi.org/10.1371/journal.pone.0077434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796482/
https://www.ncbi.nlm.nih.gov/pubmed/24155954
http://dx.doi.org/10.1371/journal.pone.0077434

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