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Utility of a Histone Deacetylase Inhibitor (PXD101) for Thyroid Cancer Treatment

BACKGROUND: We evaluated the therapeutic effects of the histone deacetylase inhibitor PXD101 alone and in combination with conventional chemotherapy in treating thyroid cancer. METHODOLOGY/PRINCIPAL FINDINGS: We studied eight cell lines from four types of thyroid cancer (papillary, follicular, anapl...

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Detalles Bibliográficos
Autores principales: Lin, Shu-Fu, Lin, Jen-Der, Chou, Ting-Chao, Huang, Yu-Yao, Wong, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796495/
https://www.ncbi.nlm.nih.gov/pubmed/24155971
http://dx.doi.org/10.1371/journal.pone.0077684