Kinetics of IL-6 Production Defines T Effector Cell Responsiveness to Regulatory T Cells in Multiple Sclerosis

In multiple sclerosis (MS) autoaggressive T effector cells (Teff) are not efficiently controlled by regulatory T cells (Treg) but the underlying mechanisms are incompletely understood. Proinflammatory cytokines are key factors facilitating Teff activity in chronic inflammation. Here we investigated...

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Detalles Bibliográficos
Autores principales: Trinschek, Bettina, Lüssi, Felix, Haas, Jürgen, Wildemann, Brigitte, Zipp, Frauke, Wiendl, Heinz, Becker, Christian, Jonuleit, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796502/
https://www.ncbi.nlm.nih.gov/pubmed/24155968
http://dx.doi.org/10.1371/journal.pone.0077634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796502/
https://www.ncbi.nlm.nih.gov/pubmed/24155968
http://dx.doi.org/10.1371/journal.pone.0077634

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