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Kinetics of IL-6 Production Defines T Effector Cell Responsiveness to Regulatory T Cells in Multiple Sclerosis
In multiple sclerosis (MS) autoaggressive T effector cells (Teff) are not efficiently controlled by regulatory T cells (Treg) but the underlying mechanisms are incompletely understood. Proinflammatory cytokines are key factors facilitating Teff activity in chronic inflammation. Here we investigated...
Autores principales: | Trinschek, Bettina, Lüssi, Felix, Haas, Jürgen, Wildemann, Brigitte, Zipp, Frauke, Wiendl, Heinz, Becker, Christian, Jonuleit, Helmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796502/ https://www.ncbi.nlm.nih.gov/pubmed/24155968 http://dx.doi.org/10.1371/journal.pone.0077634 |
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