Cargando…

The Long Noncoding RNA HOTAIR Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma Cells via downregualtion of p21(WAF1/CIP1) Expression

HOTAIR, a long intervening non-coding RNA (lincRNA), associates with the Polycomb Repressive Complex 2 (PRC2) and is reported to reprogram chromatin organization and promote tumor progression. However, little is known about the roles of this gene in the development of chemoresistance phenotype of lu...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Zhili, Sun, Ming, Lu, Kaihua, Liu, Jing, Zhang, Meiling, Wu, Weiqin, De, Wei, Wang, Zhaoxia, Wang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796503/
https://www.ncbi.nlm.nih.gov/pubmed/24155936
http://dx.doi.org/10.1371/journal.pone.0077293