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Identification of a STAT5 Target Gene, Dpf3, Provides Novel Insights in Chronic Lymphocytic Leukemia

STAT5 controls essential cellular functions and is encoded by two genes, Stat5a and Stat5b. To provide insight to the mechanisms linking hematologic malignancy to STAT5 activation/regulation of target genes, we identified STAT5 target genes and focused on Dpf3 gene, which encodes for an epigenetic f...

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Detalles Bibliográficos
Autores principales: Theodorou, Marina, Speletas, Matthaios, Mamara, Antigoni, Papachristopoulou, Georgia, Lazou, Vassiliki, Scorilas, Andreas, Katsantoni, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796511/
https://www.ncbi.nlm.nih.gov/pubmed/24155890
http://dx.doi.org/10.1371/journal.pone.0076155