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Altered Intracellular Localization of SOD1 in Leukocytes from Patients with Sporadic Amyotrophic Lateral Sclerosis

Several lines of evidence support the hypothesis of a toxic role played by wild type SOD1 (WT-SOD1) in the pathogenesis of sporadic amyotrophic lateral sclerosis (SALS). In this study we investigated both distribution and expression profile of WT-SOD1 in leukocytes from 19 SALS patients and 17 healt...

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Detalles Bibliográficos
Autores principales: Cereda, Cristina, Leoni, Emanuela, Milani, Pamela, Pansarasa, Orietta, Mazzini, Giuliano, Guareschi, Stefania, Alvisi, Elena, Ghiroldi, Andrea, Diamanti, Luca, Bernuzzi, Stefano, Ceroni, Mauro, Cova, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796534/
https://www.ncbi.nlm.nih.gov/pubmed/24155874
http://dx.doi.org/10.1371/journal.pone.0075916