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Mechanistic and environmental control of the prevalence and lifetime of amyloid oligomers
Amyloid fibrils are self-assembled protein aggregates implicated in a number of human diseases. Fragmentation-dominated models for the self-assembly of amyloid fibrils have had important successes in explaining the kinetics of amyloid fibril formation but predict fibril length distributions that do...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796876/ https://www.ncbi.nlm.nih.gov/pubmed/23695685 http://dx.doi.org/10.1038/ncomms2909 |