Cargando…
Contributions of the Complementarity Determining Regions to the Thermal Stability of a Single-Domain Antibody
Single domain antibodies (sdAbs) are the recombinantly-expressed variable domain from camelid (or shark) heavy chain only antibodies and provide rugged recognition elements. Many sdAbs possess excellent affinity and specificity; most refold and are able to bind antigen after thermal denaturation. Th...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797041/ https://www.ncbi.nlm.nih.gov/pubmed/24143255 http://dx.doi.org/10.1371/journal.pone.0077678 |