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MADM-ML, a Mouse Genetic Mosaic System with Increased Clonal Efficiency

Mosaic Analysis with Double Markers (MADM) is a mouse genetic system that allows simultaneous gene knockout and fluorescent labeling of sparse, clonally-related cells within an otherwise normal mouse, thereby circumventing embryonic lethality problems and providing single-cell resolution for phenoty...

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Detalles Bibliográficos
Autores principales: Henner, Astra, Ventura, P. Britten, Jiang, Ying, Zong, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797059/
https://www.ncbi.nlm.nih.gov/pubmed/24143253
http://dx.doi.org/10.1371/journal.pone.0077672