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MADM-ML, a Mouse Genetic Mosaic System with Increased Clonal Efficiency
Mosaic Analysis with Double Markers (MADM) is a mouse genetic system that allows simultaneous gene knockout and fluorescent labeling of sparse, clonally-related cells within an otherwise normal mouse, thereby circumventing embryonic lethality problems and providing single-cell resolution for phenoty...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797059/ https://www.ncbi.nlm.nih.gov/pubmed/24143253 http://dx.doi.org/10.1371/journal.pone.0077672 |