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Accelerated Activation of SOCE Current in Myotubes from Two Mouse Models of Anesthetic- and Heat-Induced Sudden Death

Store-operated calcium entry (SOCE) channels play an important role in Ca(2+) signaling. Recently, excessive SOCE was proposed to play a central role in the pathogenesis of malignant hyperthermia (MH), a pharmacogenic disorder of skeletal muscle. We tested this hypothesis by characterizing SOCE curr...

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Detalles Bibliográficos
Autores principales: Yarotskyy, Viktor, Protasi, Feliciano, Dirksen, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797063/
https://www.ncbi.nlm.nih.gov/pubmed/24143248
http://dx.doi.org/10.1371/journal.pone.0077633