MUC1 Regulates Expression of Multiple microRNAs Involved in Pancreatic Tumor Progression, Including the miR-200c/141 Cluster

MUC1 is a transmembrane glycoprotein that modulates transcription via its cytoplasmic domain. We evaluated the capacity of MUC1 to regulate the global transcription of microRNAs in pancreatic cancer cells expressing MUC1. Results indicated that MUC1 regulated expression of at least 103 microRNAs. We...

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Detalles Bibliográficos
Autores principales: Mohr, Ashley M., Bailey, Jennifer M., Lewallen, Michelle E., Liu, Xiang, Radhakrishnan, Prakash, Yu, Fang, Tapprich, William, Hollingsworth, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797065/
https://www.ncbi.nlm.nih.gov/pubmed/24143167
http://dx.doi.org/10.1371/journal.pone.0073306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797065/
https://www.ncbi.nlm.nih.gov/pubmed/24143167
http://dx.doi.org/10.1371/journal.pone.0073306

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