Effects of the Deletion of Early Region 4 (E4) Open Reading Frame 1 (orf1), orf1-2, orf1-3 and orf1-4 on Virus-Host Cell Interaction, Transgene Expression, and Immunogenicity of Replicating Adenovirus HIV Vaccine Vectors

The global health burden engendered by human immunodeficiency virus (HIV)-induced acquired immunodeficiency syndrome (AIDS) is a sobering reminder of the pressing need for a preventative vaccine. In non-human primate models replicating adenovirus (Ad)-HIV/SIV recombinant vaccine vectors have been sh...

Descripción completa

Detalles Bibliográficos
Autores principales: Thomas, Michael A., Song, Rui, Demberg, Thorsten, Vargas-Inchaustegui, Diego A., Venzon, David, Robert-Guroff, Marjorie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797075/
https://www.ncbi.nlm.nih.gov/pubmed/24143187
http://dx.doi.org/10.1371/journal.pone.0076344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797075/
https://www.ncbi.nlm.nih.gov/pubmed/24143187
http://dx.doi.org/10.1371/journal.pone.0076344

Ejemplares similares