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Identification of Genes Potentially Regulated by Human Polynucleotide Phosphorylase (hPNPase(old-35)) Using Melanoma as a Model
Human Polynucleotide Phosphorylase (hPNPase(old-35) or PNPT1) is an evolutionarily conserved 3′→5′ exoribonuclease implicated in the regulation of numerous physiological processes including maintenance of mitochondrial homeostasis, mtRNA import and aging-associated inflammation. From an RNase perspe...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797080/ https://www.ncbi.nlm.nih.gov/pubmed/24143183 http://dx.doi.org/10.1371/journal.pone.0076284 |