Imaging the L-Type Amino Acid Transporter-1 (LAT1) with Zr-89 ImmunoPET

The L-type amino acid transporter-1 (LAT1, SLC7A5) is upregulated in a wide range of human cancers, positively correlated with the biological aggressiveness of tumors, and a promising target for both imaging and therapy. Radiolabeled amino acids such as O-(2-[(18)F]fluoroethyl)-L-tyrosine (FET) that...

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Detalles Bibliográficos
Autores principales: Ikotun, Oluwatayo F., Marquez, Bernadette V., Huang, Chaofeng, Masuko, Kazue, Daiji, Miyamoto, Masuko, Takashi, McConathy, Jonathan, Lapi, Suzanne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797081/
https://www.ncbi.nlm.nih.gov/pubmed/24143237
http://dx.doi.org/10.1371/journal.pone.0077476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797081/
https://www.ncbi.nlm.nih.gov/pubmed/24143237
http://dx.doi.org/10.1371/journal.pone.0077476

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