Differential Activation of Wnt-β-Catenin Pathway in Triple Negative Breast Cancer Increases MMP7 in a PTEN Dependent Manner

Mutations of genes in tumor cells of Triple Negative subset of Breast Cancer (TNBC) deregulate pathways of signal transduction. The loss of tumor suppressor gene PTEN is the most common first event associated with basal-like subtype (Martins, De, Almendro, Gonen, and Park, 2012). Here we report for...

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Detalles Bibliográficos
Autores principales: Dey, Nandini, Young, Brandon, Abramovitz, Mark, Bouzyk, Mark, Barwick, Benjamin, De, Pradip, Leyland-Jones, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797090/
https://www.ncbi.nlm.nih.gov/pubmed/24143235
http://dx.doi.org/10.1371/journal.pone.0077425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797090/
https://www.ncbi.nlm.nih.gov/pubmed/24143235
http://dx.doi.org/10.1371/journal.pone.0077425

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