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NOTCH3 Is a Prognostic Factor That Promotes Glioma Cell Proliferation, Migration and Invasion via Activation of CCND1 and EGFR

Using a GWA analysis of a comprehensive glioma specimen population, we identified whole gain of chromosome 19 as one of the major chromosomal aberrations that correlates to patients’ outcomes. Our analysis of significant loci revealed for the first time NOTCH3 as one of the most significant amplific...

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Detalles Bibliográficos
Autores principales: Alqudah, Mohammad A. Y., Agarwal, Supreet, Al-Keilani, Maha S., Sibenaller, Zita A., Ryken, Timothy C., Assem, Mahfoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797092/
https://www.ncbi.nlm.nih.gov/pubmed/24143218
http://dx.doi.org/10.1371/journal.pone.0077299