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Global Expression of Molecular Transporters in the Human Vaginal Tract: Implications for HIV Chemoprophylaxis

BACKGROUND: Pre-exposure chemoprophylaxis (PrECP) using antiretroviral agents is a promising strategy for the prevention of sexual HIV transmission in women. Molecular transporters in the human vaginal tract (VT) may play a pivotal role in determining drug disposition and, consequently, pharmacodyna...

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Detalles Bibliográficos
Autores principales: Gunawardana, Manjula, Mullen, Madeline, Moss, John A., Pyles, Richard B., Nusbaum, Rebecca J., Patel, Jignesh, Vincent, Kathleen L., Wang, Charles, Guo, Chao, Yuan, Yate-Ching, Warden, Charles D., Baum, Marc M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797116/
https://www.ncbi.nlm.nih.gov/pubmed/24143220
http://dx.doi.org/10.1371/journal.pone.0077340