Downregulation of MicroRNA-9 in iPSC-Derived Neurons of FTD/ALS Patients with TDP-43 Mutations

Transactive response DNA-binding protein 43 (TDP-43) is a major pathological protein in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). There are many disease-associated mutations in TDP-43, and several cellular and animal models with ectopic overexpression of mutant TDP-43 ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhijun, Almeida, Sandra, Lu, Yubing, Nishimura, Agnes L., Peng, Lingtao, Sun, Danqiong, Wu, Bei, Karydas, Anna M., Tartaglia, Maria C., Fong, Jamie C., Miller, Bruce L., Farese, Robert V., Moore, Melissa J., Shaw, Christopher E., Gao, Fen-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797144/
https://www.ncbi.nlm.nih.gov/pubmed/24143176
http://dx.doi.org/10.1371/journal.pone.0076055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797144/
https://www.ncbi.nlm.nih.gov/pubmed/24143176
http://dx.doi.org/10.1371/journal.pone.0076055

Ejemplares similares