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The emerging and diverse roles of sirtuins in cancer: a clinical perspective

Sirtuins are a highly conserved family of nicotinamide adenine dinucleotide (NAD(+))-dependent protein lysine modifying enzymes with deacetylase, adenosine diphosphateribosyltransferase and other deacylase activities. Mammals have seven sirtuins, namely SIRT1-7. They are key regulators for a wide va...

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Detalles Bibliográficos
Autores principales: Yuan, Hongfeng, Su, Leila, Chen, Wen Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797239/
https://www.ncbi.nlm.nih.gov/pubmed/24133372
http://dx.doi.org/10.2147/OTT.S37750