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Gene expression of the IGF pathway family distinguishes subsets of gastrointestinal stromal tumors wild type for KIT and PDGFRA

Gastrointestinal stromal tumors (GISTs) arise from the interstitial cells of Cajal (ICCs) and are the most common mesenchymal neoplasm of the gastrointestinal tract. While the majority of GISTs harbor activating mutations in either the v-kit Hardy-Zuckerman feline sarcoma viral oncogene homolog (KIT...

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Detalles Bibliográficos
Autores principales: Beadling, Carol, Patterson, Janice, Justusson, Emily, Nelson, Dylan, Pantaleo, Maria A., Hornick, Jason L., Chacón, Matias, Corless, Christopher L., Heinrich, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797556/
https://www.ncbi.nlm.nih.gov/pubmed/24133624
http://dx.doi.org/10.1002/cam4.57