Bisebromoamide, an extract from Lyngbya species, induces apoptosis through ERK and mTOR inhibitions in renal cancer cells

Advanced renal cell carcinoma (RCC) remains an incurable disease, and newer anticancer drugs are needed. Bisebromoamide, a novel cytotoxic peptide, was isolated from the marine cyanobacterium Lyngbya species at our laboratory in 2009. This compound specifically inhibited the phosphorylation of ERK i...

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Detalles Bibliográficos
Autores principales: Suzuki, Kenjiro, Mizuno, Ryuichi, Suenaga, Kiyotake, Teruya, Toshiaki, Tanaka, Nobuyuki, Kosaka, Takeo, Oya, Mototsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797566/
https://www.ncbi.nlm.nih.gov/pubmed/24133625
http://dx.doi.org/10.1002/cam4.53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797566/
https://www.ncbi.nlm.nih.gov/pubmed/24133625
http://dx.doi.org/10.1002/cam4.53

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