Identification of Semicarbazones, Thiosemicarbazones and Triazine Nitriles as Inhibitors of Leishmania mexicana Cysteine Protease CPB

Cysteine proteases of the papain superfamily are present in nearly all eukaryotes. They play pivotal roles in the biology of parasites and inhibition of cysteine proteases is emerging as an important strategy to combat parasitic diseases such as sleeping sickness, Chagas’ disease and leishmaniasis....

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Detalles Bibliográficos
Autores principales: Schröder, Jörg, Noack, Sandra, Marhöfer, Richard J., Mottram, Jeremy C., Coombs, Graham H., Selzer, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797739/
https://www.ncbi.nlm.nih.gov/pubmed/24146999
http://dx.doi.org/10.1371/journal.pone.0077460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797739/
https://www.ncbi.nlm.nih.gov/pubmed/24146999
http://dx.doi.org/10.1371/journal.pone.0077460

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