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Alteration of Innate Immunity by Donor IL-6 Deficiency in a Presensitized Heart Transplant Model

Engraftment of IL-6 deficient donor into wild-type recipient could significantly improve allograft survival through T cell lineage particularly regulatory T cells (Tregs) in non-sensitized transplant host. However, its effect on innate immune responses remains uncertain. Our data revealed that donor...

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Detalles Bibliográficos
Autores principales: Ge, Fangmin, Yuan, Shunzong, Su, Lida, Shen, Zhonghua, He, Aibin, Huang, Tao, Gong, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797753/
https://www.ncbi.nlm.nih.gov/pubmed/24147024
http://dx.doi.org/10.1371/journal.pone.0077559