Cargando…

Identification of Cisplatin-Regulated Metabolic Pathways in Pluripotent Stem Cells

The chemotherapeutic compound, cisplatin causes various kinds of DNA lesions but also triggers other pertubations, such as ER and oxidative stress. We and others have shown that treatment of pluripotent stem cells with cisplatin causes a plethora of transcriptional and post-translational alterations...

Descripción completa

Detalles Bibliográficos
Autores principales: von Stechow, Louise, Ruiz-Aracama, Ainhoa, van de Water, Bob, Peijnenburg, Ad, Danen, Erik, Lommen, Arjen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797786/
https://www.ncbi.nlm.nih.gov/pubmed/24146875
http://dx.doi.org/10.1371/journal.pone.0076476