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Identification of Cisplatin-Regulated Metabolic Pathways in Pluripotent Stem Cells
The chemotherapeutic compound, cisplatin causes various kinds of DNA lesions but also triggers other pertubations, such as ER and oxidative stress. We and others have shown that treatment of pluripotent stem cells with cisplatin causes a plethora of transcriptional and post-translational alterations...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797786/ https://www.ncbi.nlm.nih.gov/pubmed/24146875 http://dx.doi.org/10.1371/journal.pone.0076476 |