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Regulation of the Expression of Chaperone gp96 in Macrophages and Dendritic Cells
The chaperone function of the ER-residing heat shock protein gp96 plays an important role in protein physiology and has additionally important immunological functions due to its peptide-binding capacity. Low amounts of gp96 stimulate immunity; high quantities induce tolerance by mechanisms not fully...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797789/ https://www.ncbi.nlm.nih.gov/pubmed/24146856 http://dx.doi.org/10.1371/journal.pone.0076350 |