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Different Involvement of Promoter Methylation in the Expression of Organic Cation/Carnitine Transporter 2 (OCTN2) in Cancer Cell Lines

Organic cation/carnitine transporter 2 (OCTN2) is responsible for the cellular uptake of the antineoplastic agent, oxaliplatin. Epigenetic modification is a possible mechanism of altered drug-transporter expression in cancers, leading to altered efficacy of chemotherapeutic drugs. However, the mecha...

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Detalles Bibliográficos
Autores principales: Qu, Qiang, Qu, Jian, Zhan, Min, Wu, Lan-Xiang, Zhang, Yi-Wen, Lou, Xiao-Ya, Fu, Li-Juan, Zhou, Hong-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797819/
https://www.ncbi.nlm.nih.gov/pubmed/24146874
http://dx.doi.org/10.1371/journal.pone.0076474