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Posttranslational Modifications of Proopiomelanocortin in Vertebrates and Their Biological Significance

Proopiomelanocortin (POMC) is the precursor of several peptide hormones generated in the pituitary gland. After biosynthesis, POMC undergoes several posttranslational modifications, including proteolytic cleavage, acetylation, amidation, phosphorylation, glycosylation, and disulfide linkage formatio...

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Detalles Bibliográficos
Autores principales: Takahashi, Akiyoshi, Mizusawa, Kanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797980/
https://www.ncbi.nlm.nih.gov/pubmed/24146662
http://dx.doi.org/10.3389/fendo.2013.00143