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Posttranslational Modifications of Proopiomelanocortin in Vertebrates and Their Biological Significance
Proopiomelanocortin (POMC) is the precursor of several peptide hormones generated in the pituitary gland. After biosynthesis, POMC undergoes several posttranslational modifications, including proteolytic cleavage, acetylation, amidation, phosphorylation, glycosylation, and disulfide linkage formatio...
Autores principales: | Takahashi, Akiyoshi, Mizusawa, Kanta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797980/ https://www.ncbi.nlm.nih.gov/pubmed/24146662 http://dx.doi.org/10.3389/fendo.2013.00143 |
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