Cargando…

p53 Regulates Period2 Expression and the Circadian Clock

The mechanistic interconnectivity between circadian regulation and the genotoxic stress response remains poorly understood. Here we show that the expression of Period 2 (Per2), a circadian regulator, is directly regulated by p53 binding to a response element in the Per2 promoter. This p53 response e...

Descripción completa

Detalles Bibliográficos
Autores principales: Miki, Takao, Matsumoto, Tomoko, Zhao, Zhaoyang, Lee, Cheng Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798035/
https://www.ncbi.nlm.nih.gov/pubmed/24051492
http://dx.doi.org/10.1038/ncomms3444